Presentation
25g/100mL
SAS
Role
- Management of severe cyanide poisoning evidenced by altered level of consciousness, seizures, hypotension or significant acidosis.
- Must be given with either hydroxocobalamin (preferred) or sodium nitrite.
Dose
12.5g IV (child 400mg/kg) in 200mL 5% glucose over 30 min.
Stocking recommendations
Tertiary centre | Regional centre | Rural centre | Remote centre |
---|---|---|---|
25g | 25g | 0-25g | 0 |
Rationale
If available, hydroxocobalamin is the preferred antidote for cyanide poisoning. Sodium thiosulfate plus sodium nitrite are an acceptable alternative if hydroxocobalamin is unavailable.
Disclaimer
Last updated: July 2023